CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11996
Family Name Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell growth factor receptor Kit ligand N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethylpiperidin-4-yl)oxypyridine-2-carboxamide family
No. of Seeds 11 No. of Other Members 0
Family Centroid CFAMM00413212 Functional Category Bioactive
Superfamily Diacylglycerol O-acyltransferase 1 and cAMP Binder Superfamily
Class Class 2433

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Receptor-type tyrosine-protein kinase FLT3 and Macrophage colo... 9 8
Receptor-type tyrosine-protein kinase FLT3 ligand SureCN132348... 2 1
Platelet-derived growth factor receptor beta ligand N-(4,5-dim... 5 1


External ID

Functional Category

Molecule Name

CFAMM00413214 CHEMBL2206277 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1,2,2,6,6-pentamethylpiperidin-4-yl)oxypyridine-2-carboxamide
CFAMM00413213 CHEMBL2203435 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-propan-2-ylpiperidin-4-yl)oxypyridine-2-carboxamide
CFAMM00413212 CHEMBL2203434 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethylpiperidin-4-yl)oxypyridine-2-carboxamide
CFAMM00413211 CHEMBL2203437 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-tert-butylpiperidin-4-yl)oxypyridine-2-carboxamide
CFAMM00413210 CHEMBL2203436 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]oxypyridine-2-carboxamide
CFAMM00413216 CHEMBL2206278 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-ethyl-2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide
CFAMM00413209 CHEMBL2203438 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(1-cyclopropylpiperidin-4-yl)oxypyridine-2-carboxamide
CFAMM00413215 CHEMBL2206279 Bioactive N-[4-[(5-tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-5-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridine-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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