CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12004
Family Name Progesterone receptor ligand N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]ethanesulfonamide family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00413235 Functional Category Bioactive
Superfamily Progesterone receptor and Androgen receptor Binder Superfamily
Class Class 3431

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
D(1B) dopamine receptor Ligand LE-300 Family 65 452
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
5-hydroxytryptamine receptor 6 Ligand 4-(1h-indol-1-ylsulfonyl... 7 79
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Mineralocorticoid receptor and Androgen receptor Ligand WAY-25... 10 26
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor Quinol... 4 13
5-hydroxytryptamine receptor 6 Ligand 6-tosyl-1,2,3,4,5,6-hexa... 4 22
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 3
Progesterone receptor and Androgen receptor ligand 5-[4-[(Z)-C... 2 5
Progesterone receptor and Mineralocorticoid receptor ligand AG... 6 1
5-hydroxytryptamine receptor 6 ligand 1-(4-chlorophenyl)sulfon... 8 4
5-hydroxytryptamine receptor 6 ligand 9-(benzenesulfonyl)-N,N-... 7 1
5-hydroxytryptamine receptor 6 ligand 5-[3-(2-aminoethyl)indol... 1 0


External ID

Functional Category

Molecule Name

CFAMM00413236 CHEMBL2203823 Bioactive N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]propane-1-sulfonamide
CFAMM00413235 CHEMBL2203821 Bioactive N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]ethanesulfonamide
CFAMM00413233 CHEMBL2203825 Bioactive N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]propane-2-sulfonamide
CFAMM00413242 CHEMBL2203833 Bioactive N-[4-(5-cyano-1-methylpyrrol-2-yl)-3-fluorophenyl]methanesulfonamide
CFAMM00413241 CHEMBL2203819 Bioactive N-[4-(5-cyano-1-methylpyrrol-2-yl)phenyl]methanesulfonamide
CFAMM00413238 CHEMBL2203832 Bioactive N-[4-(5-cyano-1-methylpyrrol-2-yl)-3-fluorophenyl]ethanesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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