CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12008
Family Name Glucocorticoid receptor ligand 5-[(3-methylphenyl)methyl]-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00413277 Functional Category Bioactive
Superfamily Glucocorticoid receptor Binder Superfamily 10
Class Class 3995

Cousin Family NamesSeedsMembers
Alpha-1A adrenergic receptor Ligand SNAP-6201 Family 41 94
Reverse transcriptase Inhibitor Emivirine Family 5 12
Cellular tumor antigen p53 and Retinal dehydrogenase 1 inhibit... 1 4
Dipeptidyl peptidase 4 inhibitor SureCN389715 family 2 2
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 9 21
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 3 1
Gonadotropin-releasing hormone receptor and Cytochrome P450 3A... 7 8
Glucocorticoid receptor ligand 5-[(2,5-dichlorophenyl)methyl]-... 3 4
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 5 7
Alpha-1A adrenergic receptor and Histamine H1 receptor ligand ... 13 1
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 20 2


External ID

Functional Category

Molecule Name

CFAMM00413277 CHEMBL2204040 Bioactive 5-[(3-methylphenyl)methyl]-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione
CFAMM00413276 CHEMBL2204043 Bioactive 6-(4-phenylcyclohexyl)-5-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrimidine-2,4-dione
CFAMM00413282 CHEMBL2204038 Bioactive 5-benzyl-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione
CFAMM00413279 CHEMBL2204062 Bioactive 3-[2-(dimethylamino)ethyl]-5-[(3-methylphenyl)methyl]-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



46158 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543