CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12011
Family Name Angiopoietin-1 receptor and Vascular endothelial growth factor receptor 2 ligand CHEMBL401881 family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00413310 Functional Category Bioactive
Superfamily Beta-lactamase and Vasopressin V2 receptor Binder Superfamily
Class Class 3314

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Vascular endothelial growth factor receptor 2 and Angiopoietin... 4 1
Serine/threonine-protein kinase mTOR inhibitor AGN-PC-093LHN f... 3 2
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 3 5
Protein kinase C beta type and Protein kinase C delta type inh... 1 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Histone deacetylase 1 inhibitor N-hydroxy-5-[1-[2-[(1-methylin... 4 1
Vascular endothelial growth factor receptor 2 and Angiopoietin... 14 0
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 2 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413310 CHEMBL401881 Bioactive CHEMBL401881
CFAMM00413309 CHEMBL426703 Bioactive CHEMBL426703

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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