CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12016
Family Name Sodium-dependent serotonin transporter and 5-hydroxytryptamine receptor 3A ligand 1-[2-(4-methoxyphenyl)sulfanylphenyl]piperazine;hydrochloride family
No. of Seeds 3 No. of Other Members 14
Family Centroid CFAMM00413348 Functional Category Bioactive with Human Metabolite
Superfamily 5-hydroxytryptamine receptor 3A and Sodium-dependent serotonin transporter Binder Superfamily
Class Class 4880

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 6 Ligand SB-357134 Family 13 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 9
5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4... 7 2
Bifunctional epoxide hydrolase 2 inhibitor SureCN2729784 family 3 9
5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin... 6 3
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family 9 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 10 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
Sodium-dependent serotonin transporter and Sodium-dependent no... 9 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 3 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1
Melatonin receptor type 1B ligand SureCN8150656 family 2 0
Alpha-synuclein inhibitor 3-(2-fluoroethoxy)-7-nitro-10H-pheno... 3 0


External ID

Functional Category

Molecule Name

CFAMM00413351 CHEMBL2204358 Bioactive 1-[2-(2,4-dimethoxyphenyl)sulfanylphenyl]piperazine;hydrochloride
CFAMM00413348 CHEMBL2205042 Bioactive 1-[2-(4-methoxyphenyl)sulfanylphenyl]piperazine;hydrochloride

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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