CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12019
Family Name Prostaglandin D2 receptor 2 and Cytochrome P450 2C19 ligand 2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid family
No. of Seeds 6 No. of Other Members 13
Family Centroid CFAMM00413377 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor 2 and Cytochrome P450 2C19 Binder Superfamily
Class Class 926

Cousin Family NamesSeedsMembers
Thromboxane A2 receptor Ligand Ramatroban Family 13 49
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
Setipiprant family 5 118
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Adenosine receptor A1 and Adenosine receptor A2a Ligand FK-838... 4 19
Fatty acid-binding protein, adipocyte and Fatty acid-binding p... 3 11
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 2
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 36
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 5 8
Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-2-methyl-3-[(4-... 3 5
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... 3 8
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 3 5
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Prostaglandin D2 receptor 2 and Prostaglandin G/H synthase 1 l... 3 17
Prostaglandin D2 receptor 2 ligand SureCN317401 family 3 8
Prostaglandin D2 receptor 2 ligand 2-[(3R)-3-(3,3-diphenylprop... 1 0
Prostaglandin D2 receptor 2 ligand 2-[3-[(3-chlorophenyl)-meth... 1 0
Prostaglandin D2 receptor 2 ligand 2-[5-fluoro-3-[[1-[[4-(2-hy... 2 0
Prostaglandin D2 receptor 2 ligand 2-[3-[(E)-2-cyano-3-(N-meth... 9 9
Substance-P receptor ligand AGN-PC-004REJ family 3 0


External ID

Functional Category

Molecule Name

CFAMM00413369 CHEMBL2204473 Bioactive 2-[5-fluoro-3-[[1-[(3-fluoropyridin-4-yl)methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
CFAMM00413368 CHEMBL2204474 Bioactive 2-[5-fluoro-2-methyl-3-[[6-oxo-1-[(2,4,5-trifluorophenyl)methyl]pyridazin-3-yl]methyl]indol-1-yl]acetic acid
CFAMM00413372 CHEMBL2205146 Bioactive 2-[3-[(1-benzyl-6-oxopyridazin-3-yl)methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00413371 CHEMBL2204470 Bioactive 2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxo-4,5-dihydropyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00413377 CHEMBL2204469 Bioactive 2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
CFAMM00413376 CHEMBL2204471 Bioactive 2-[3-[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]-5-fluoro-2-methylindol-1-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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