CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12031
Family Name Peroxisome proliferator-activated receptor alpha and Peroxisome proliferator-activated receptor gamma ligand 2-[4-[[furan-2-ylmethyl-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino]methyl]-2-methylphenoxy]-2-methylpropanoic acid family
No. of Seeds 5 No. of Other Members 2
Family Centroid CFAMM00067356 Functional Category Bioactive
Superfamily Peroxisome proliferator-activated receptor alpha and Peroxisome proliferator-activated receptor gamma Binder Superfamily 3
Class Class 2976

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Peroxisome proliferator-activated receptor alpha Ligand Alegli... 29 7
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Neutrophil elastase Inhibitor Cbz-val-pro-val-(2-benzoxazole) ... 32 64
Leukotriene A-4 hydrolase Inhibitor 2-[4-(2-azepan-1-ylethoxy)... 5 15
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Phospholipase A2 inhibitor SureCN7046992 family 2 3
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 7 1
Sphingosine 1-phosphate receptor 1 ligand AGN-PC-00DWQL family 2 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 3
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 3
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 5 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 1
Peroxisome proliferator-activated receptor alpha ligand 5-[4-[... 1 0
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 1 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 3
Protein farnesyltransferase subunit beta and Protein farnesylt... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413418 CHEMBL2204595 Bioactive 2-[4-[[furan-2-ylmethyl-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino]methyl]-2,6-dimethylphenoxy]-2-methylpropanoic acid
CFAMM00413419 CHEMBL2204598 Bioactive 2-[2-chloro-4-[[furan-2-ylmethyl-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino]methyl]phenoxy]-2-methylpropanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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