CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12041
Family Name Glucose-dependent insulinotropic receptor ligand 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]pyrazole-3-carbonitrile family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00413482 Functional Category Bioactive
Superfamily cAMP and Glucokinase Binder Superfamily
Class Class 855

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Ibrutinib family 2 27
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 4
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Voltage-dependent calcium channel subunit alpha-2/delta-1 and ... 9 15
Corticotropin-releasing factor receptor 1 ligand 5-N-(2-chloro... 7 1
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 2
TGF-beta receptor type-1 ligand N-(4-methoxyphenyl)-3-(6-methy... 5 2
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 0
Motilin receptor ligand SureCN2012437 family 4 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Adenosine receptor A2a ligand 8-(3-fluorophenyl)-3-[2-[4-[4-(2... 5 0
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 7 5
Oxytocin receptor and Vasopressin V1a receptor ligand AGN-PC-0... 4 3
Voltage-dependent calcium channel subunit alpha-2/delta-1 liga... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413482 CHEMBL2204984 Bioactive 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]pyrazole-3-carbonitrile
CFAMM00413481 CHEMBL2204985 Bioactive 4-[(4-cyano-2-fluorophenoxy)methyl]-2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]pyrazole-3-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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