CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12056
Family Name Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chloro-3-[[4-[2-(diethylamino)ethoxy]phenyl]methylidene]-1H-indol-2-one family
No. of Seeds 1 No. of Other Members 4
Family Centroid CFAMM00413611 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and Nuclear receptor ROR-gamma Binder Superfamily 21
Class Class 1458

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Aplindore Fumarate Family 2 30
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 7 9
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Potassium voltage-gated channel subfamily H member 2 and Melan... 9 4
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 12
Cathepsin L1 and Cathepsin S inhibitor arylaminoethyl amide, 5... 4 5
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2R... 8 9
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Bifunctional epoxide hydrolase 2 and RAF proto-oncogene serine... 4 10
Poly [ADP-ribose] polymerase 1 inhibitor 6-[[4-(4-chlorophenyl... 1 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 4 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 4 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-00RZQT family 3 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJY family 5 4
Thioredoxin glutathione reductase and Microtubule-associated p... 1 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 3
Sodium channel protein type 1 subunit alpha and Sodium channel... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413611 CHEMBL2206008 Bioactive (3Z)-5-chloro-3-[[4-[2-(diethylamino)ethoxy]phenyl]methylidene]-1H-indol-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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