CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12061
Family Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A and cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor [1-[3-[4-(1,3-benzoxazol-2-ylamino)phenoxy]pyrazin-2-yl]piperidin-4-yl]methanol family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00413636 Functional Category Bioactive
Superfamily Diacylglycerol O-acyltransferase 1 and cAMP Binder Superfamily
Class Class 2433

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 37
Vascular endothelial growth factor receptor 1 and Vascular end... 4 44
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
Fatty-acid amide hydrolase 1 inhibitor 3-[(3R)-1-[4-(1-benzofu... 4 4
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 8 8
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Fatty-acid amide hydrolase 1 inhibitor 2-(1,3-dihydroisoindol-... 2 3
Prothrombin inhibitor SureCN6925359 family 6 18
Tubulin beta-4A chain and Tubulin beta-2B chain inhibitor N-(2... 1 4
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Vascular endothelial growth factor receptor 2 ligand N-[4-chlo... 2 0
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 5 0
Mitogen-activated protein kinase 14 inhibitor 4-[4-(4-fluoroph... 1 5
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Reverse transcriptase/RNaseH inhibitor AC1LAJTX family 2 0
C-C chemokine receptor type 3 ligand SureCN6338683 family 1 2
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077D0D family 3 0
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 1 0
Sorbitol dehydrogenase inhibitor SureCN6298924 family 4 4
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413636 CHEMBL2206220 Bioactive [1-[3-[4-(1,3-benzoxazol-2-ylamino)phenoxy]pyrazin-2-yl]piperidin-4-yl]methanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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