CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12063
Family Name Histamine H3 receptor ligand 2-[[3-[4-(pyrrolidin-1-ylmethyl)phenyl]cyclobutyl]methoxy]pyrimidine family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00413644 Functional Category Bioactive
Superfamily Histamine H3 receptor ligand 2-[[3-[4-(pyrrolidin-1-ylmethyl)phenyl]cyclobutyl]methoxy]pyrimidine Superfamily
Class Class 4883

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
Histamine H3 receptor ligand 2-pyrimidin-5-yl-4-[4-(2-pyrrolid... 1 0


External ID

Functional Category

Molecule Name

CFAMM00413644 CHEMBL2206289 Bioactive 2-[[3-[4-(pyrrolidin-1-ylmethyl)phenyl]cyclobutyl]methoxy]pyrimidine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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