CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12072
Family Name Muscarinic acetylcholine receptor M3 and Muscarinic acetylcholine receptor M2 ligand propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-(cyclohexylmethyl)piperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate family
No. of Seeds 4 No. of Other Members 22
Family Centroid CFAMM00413722 Functional Category Bioactive
Superfamily Neutrophil elastase Inhibitor FR-901277 Superfamily
Class Class 1350

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2... 2 8
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 12 13
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-(1,3-ben... 5 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752MU... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413723 CHEMBL2206591 Bioactive propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-(1,2,3,4-tetrahydronaphthalen-2-ylmethyl)piperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
CFAMM00413703 CHEMBL2206586 Bioactive (4-chlorophenyl)methyl-[3-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]-2,2-dimethylpropyl]-dimethylazanium
CFAMM00413709 CHEMBL480877 Bioactive ethyl 4-[[(2S)-1-[[1-[(3-chlorophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
CFAMM00413722 CHEMBL2206590 Bioactive propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-(cyclohexylmethyl)piperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26831 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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