CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12073
Family Name Muscarinic acetylcholine receptor M3 and Muscarinic acetylcholine receptor M2 ligand propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[4-methyl-4-(2-phenylethyl)piperazin-4-ium-1-yl]-1-oxopropan-2-yl]carbamoylamino]benzoate family
No. of Seeds 12 No. of Other Members 13
Family Centroid CFAMM00306812 Functional Category Bioactive with Natural Product
Superfamily Neutrophil elastase Inhibitor FR-901277 Superfamily
Class Class 1350

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase SYK Inhibitor N-benzyl-4-(2,5-dihydrox... 1 4
Substance-K receptor Ligand MEN-14933 Family 13 154
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Beta-1 adrenergic receptor ligand 4-[2-[[(2S)-3-(2-cyano-5-flu... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Gastrin/cholecystokinin type B receptor ligand 1-[3-[[2-(3-met... 2 12
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2... 2 8
Bifunctional epoxide hydrolase 2 inhibitor dimethyl 5-[4-[(4-m... 1 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 22
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-(1,3-ben... 5 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7496449 f... 3 2
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 10 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 7
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(2-chlo... 2 0
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752MU... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413725 CHEMBL540359 Bioactive propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[(3S)-1-[(3-hydroxyphenyl)methyl]-1-methylpiperidin-1-ium-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate;iodide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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