CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12079
Family Name Urokinase plasminogen activator surface receptor ligand ethyl 2-[2-[(13-oxo-11H-quinoxalino[2,3-b][1,4]benzodiazepin-6-yl)methyl]benzimidazol-1-yl]acetate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00413767 Functional Category Bioactive
Superfamily Beta-lactamase and Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Binder Superfamily
Class Class 716

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Histamine H1 receptor Ligand Mizolastine Family 14 603
Prothrombin Inhibitor Dabigatran Family 7 182
BIBT986 family 7 96
SB989 family 17 91
CC-486 family 7 103
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Histone deacetylase 1 and Histone deacetylase 8 inhibitor (E)-... 3 0
Poly [ADP-ribose] polymerase 1 inhibitor SureCN6202744 family 4 2
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... 10 19
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Histamine H1 receptor and Potassium voltage-gated channel subf... 1 2
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 1
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
Disintegrin and metalloproteinase domain-containing protein 17... 10 4
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413767 CHEMBL2206685 Bioactive ethyl 2-[2-[(13-oxo-11H-quinoxalino[2,3-b][1,4]benzodiazepin-6-yl)methyl]benzimidazol-1-yl]acetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26833 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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