CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12107
Family Name Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A ligand 3-[[4-[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]methyl]-1,2,4-oxadiazole family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00413891 Functional Category Bioactive
Superfamily Lysosomal Pro-X carboxypeptidase and Aurora kinase A Binder Superfamily
Class Class 3234

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Adenosine receptor A2a and Adenosine receptor A3 Ligand 5-buty... 3 18
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Adenosine receptor A2b Ligand CVT-6694 Family 1 22
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Adenosine receptor A3 and Adenosine receptor A2a ligand 5-buty... 3 13
Aurora kinase B inhibitor AGN-PC-07ZZ0Y family 2 12
Adenosine receptor A3 and Adenosine receptor A2a ligand SureCN... 8 7
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 3 11
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 13
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 2
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413893 CHEMBL2207499 Bioactive 3-[[4-[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]methyl]-4-methyl-1,2,5-oxadiazole
CFAMM00413892 CHEMBL2207501 Bioactive 3-[[4-[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]methyl]-5-methyl-1,2,4-oxadiazole
CFAMM00413891 CHEMBL2207500 Bioactive 3-[[4-[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]piperazin-1-yl]methyl]-1,2,4-oxadiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46113 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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