CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12119
Family Name Leukotriene A-4 hydrolase and Potassium voltage-gated channel subfamily H member 2 ligand 1-[1-[2-[4-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)phenoxy]ethyl]piperidin-4-yl]pyrrolidin-2-one family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00413947 Functional Category Bioactive
Superfamily Leukotriene A-4 hydrolase and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily
Class Class 1699

Cousin Family NamesSeedsMembers
Leukotriene A-4 hydrolase inhibitor 1-[1-[[4-([1,3]thiazolo[4,... 9 13
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 3
Vascular endothelial growth factor receptor 2 ligand aminothia... 1 1


External ID

Functional Category

Molecule Name

CFAMM00413945 CHEMBL2207736 Bioactive 2-[4-(2-piperidin-1-ylethoxy)phenoxy]-[1,3]thiazolo[4,5-b]pyridine
CFAMM00413944 CHEMBL2207741 Bioactive N-[8-[2-[4-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)phenoxy]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]acetamide
CFAMM00413943 CHEMBL2207740 Bioactive 1-[5-[2-[4-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)phenoxy]ethyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethanone
CFAMM00413947 CHEMBL2207738 Bioactive 1-[1-[2-[4-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)phenoxy]ethyl]piperidin-4-yl]pyrrolidin-2-one
CFAMM00413946 CHEMBL2207739 Bioactive 1-[2-[2-[4-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)phenoxy]ethyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]ethanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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