CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12121
Family Name 5-hydroxytryptamine receptor 6 ligand 1-(2-bromo-4-methoxyphenyl)sulfonyl-4-[(4-methylpiperazin-1-yl)methyl]indole family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00413948 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 ligand 1-(2-bromo-4-methoxyphenyl)sulfonyl-4-[(4-methylpiperazin-1-yl)methyl]indole Superfamily
Class Class 3318

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
Apricoxib family 8 77
Indeglitazar family 3 39
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 3
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-m... 2 12
Prostaglandin G/H synthase 2 Inhibitor 5-methoxy-2-(4-(methyls... 3 12
5-hydroxytryptamine receptor 6 ligand N-[3-[[(2R)-1-methylpyrr... 6 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 5
Cannabinoid receptor 2 ligand AGN-PC-09M5M9 family 1 0
5-hydroxytryptamine receptor 6 ligand SureCN5502542 family 4 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 15
5-hydroxytryptamine receptor 6 ligand 1-[9-(benzenesulfonyl)-6... 11 2
5-hydroxytryptamine receptor 6 ligand SureCN5498885 family 5 4
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Sodium-dependent serotonin transporter and Alpha-1B adrenergic... 2 0
5-hydroxytryptamine receptor 6 ligand SureCN5253197 family 4 2
5-hydroxytryptamine receptor 6 ligand 9-(4-methoxyphenyl)sulfo... 1 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Growth hormone secretagogue receptor type 1 ligand SureCN47965... 3 1
D(2) dopamine receptor and D(4) dopamine receptor ligand AGN-P... 1 0
5-hydroxytryptamine receptor 6 ligand 1-[9-(2,5-dimethoxypheny... 2 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Oxytocin receptor and Vasopressin V1a receptor ligand 4-methox... 9 8
5-hydroxytryptamine receptor 6 and Cytochrome P450 3A4 ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413950 CHEMBL96745 Bioactive AGN-PC-074QOS
CFAMM00413948 CHEMBL2207768 Bioactive 1-(2-bromo-4-methoxyphenyl)sulfonyl-4-[(4-methylpiperazin-1-yl)methyl]indole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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