CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1214
Family Name 5-hydroxytryptamine receptor 1A ligand (2S)-1-[(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-yl]-3-(1H-indol-4-yloxy)propan-2-ol family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00320672 Functional Category Bioactive
Superfamily Sodium/glucose cotransporter 2 and Sodium/glucose cotransporter 1 Binder Superfamily
Class Class 284

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Na+-K+-ATPase transmembrane protein Inhibitor Sanguinarine Family 8 20
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
Platelet-derived growth factor receptor beta and Epidermal gro... 3 7
Alpha-1A adrenergic receptor Ligand RS-17053 Family 9 6
Acetylcholinesterase and Cholinesterase Inhibitor 1,4-di(berbe... 5 0
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 17 69
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 7 11
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 2 10
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 36 18
Prelamin-A/C inhibitor 1-[(3,4-dimethoxyphenethyl)amino]-3-(1H... 1 2
Butyrylcholinesterase and Acetylcholinesterase inhibitor AGN-P... 9 24
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 0
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00320673 CHEMBL444794 Bioactive 1-[6-[(3R,4S)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-yl]hexylamino]-3-(1H-indol-4-yloxy)propan-2-ol
CFAMM00320672 CHEMBL113752 Bioactive (2S)-1-[(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-yl]-3-(1H-indol-4-yloxy)propan-2-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27047 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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