CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12145
Family Name Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00414070 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 99
Class Class 4584

Cousin Family NamesSeedsMembers
Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 12 44
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Fatty-acid amide hydrolase 1 Inhibitor 2-fluorophenyl 4-(octyl... 15 9
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Beta-1 adrenergic receptor ligand 1-[2-[[(2S)-3-(2-cyanophenox... 10 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 10
Transient receptor potential cation channel subfamily V member... 3 15
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 11 12
Gonadotropin-releasing hormone receptor ligand SureCN5756131 f... 5 7
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 2 3
Bifunctional epoxide hydrolase 2 inhibitor 1-(1-adamantyl)-3-[... 2 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-[(4... 4 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor [4-[(4... 10 0
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-[4-[3... 2 0
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 1 0
Transient receptor potential cation channel subfamily M member... 2 13
Alpha-1D adrenergic receptor and D(2) dopamine receptor ligand... 3 0
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 1 0
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJY family 5 4
Histamine H3 receptor ligand AGN-PC-07ZCFA family 1 0
C-C chemokine receptor type 3 ligand SureCN6700764 family 2 2
Menin and Histone-lysine N-methyltransferase 2A inhibitor CHEM... 1 0
4,4,6-trimethyl-1,3-dihydroimidazo[1,2-a]indol-2-one NP ZINC02... 37 0
8,10,10-trimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one NP... 14 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414067 CHEMBL374730 Bioactive AGN-PC-00C0ZG
CFAMM00414070 CHEMBL221737 Bioactive SureCN3178516
CFAMM00414068 CHEMBL221015 Bioactive SureCN3179791

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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