CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12153
Family Name Vascular endothelial growth factor receptor 2 ligand AC1NS6KN family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00414131 Functional Category Bioactive
Superfamily Histamine H3 receptor Ligand 2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridine Superfamily
Class Class 2616

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Cyclin-dependent kinase 2 Inhibitor 4-(2,4-dimethyl-thiazol-5-... 2 14
Metabotropic glutamate receptor 5 Ligand N-[4-(3-pyridylethyny... 2 10
Vascular endothelial growth factor receptor 2 Ligand 3-(4-amin... 2 5
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 4 23
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor Ligand PD-135146 Family 5 11
Deoxycytidine kinase inhibitor AGN-PC-07Z9B3 family 2 7
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 2 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 6
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 6 11
Platelet-activating factor receptor ligand Foropafant family 2 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 inhibitor 3-[5-[2-[(4-mor... 2 3
Serine/threonine-protein kinase Chk1 inhibitor 5-[5-(1-methylp... 3 2
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Vascular endothelial growth factor receptor 2 ligand AC1NS6KZ ... 1 0
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(1,4-di... 3 3
High affinity nerve growth factor receptor and Hepatocyte grow... 6 8
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 1
Cyclin-dependent kinase 5 and G1/S-specific cyclin-E1 inhibito... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414132 CHEMBL222852 Bioactive AC1NS6KW
CFAMM00414131 CHEMBL375306 Bioactive AC1NS6KN
CFAMM00414130 CHEMBL373693 Bioactive AC1NS6KK
CFAMM00414133 CHEMBL221468 Bioactive AC1NS6KQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27668 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543