CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12154
Family Name Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyridin-4-ylphenyl)-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00414147 Functional Category Bioactive
Superfamily Coagulation factor X and Beta-lactamase Binder Superfamily
Class Class 1209

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor M55113 Family 1 8
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Neuropeptide Y receptor type 5 ligand 2-[4-(benzenesulfonamido... 2 27
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(6-aminopyr... 1 4
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Coagulation factor X inhibitor 7-(6-chloronaphthalen-2-yl)sulf... 1 4
Coagulation factor X inhibitor 6-chloro-N-[(3S)-1-[4-[2-[(dime... 5 8
Disintegrin and metalloproteinase domain-containing protein 17... 5 9
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 3
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 4
Neuropeptide Y receptor type 5 ligand 2-(6-chloroindol-1-yl)-N... 4 23
Coagulation factor X inhibitor SureCN1652565 family 3 19
Coagulation factor X inhibitor SureCN4172349 family 7 3
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 3 2
Coagulation factor X and Prothrombin inhibitor SureCN8243313 f... 10 8
Coagulation factor X and Prothrombin inhibitor SureCN8237487 f... 16 1
Collagenase 3 and Neutrophil collagenase inhibitor (2R)-N-hydr... 1 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(3,5-di... 4 8
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 2 4
Coagulation factor X inhibitor 5-chloro-N-[1-[4-[2-[(dimethyla... 4 0
Coagulation factor X and Anionic trypsin inhibitor Sulfonamido... 2 4
Coagulation factor X inhibitor [1-[4-[3-[(6-chloronaphthalen-2... 2 0
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 1 3
P2X purinoceptor 7 inhibitor AGN-PC-015BSR family 1 0
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 2 0
Coagulation factor X inhibitor 3-(6-chloronaphthalen-2-yl)sulf... 5 10
Coagulation factor X inhibitor ethyl 2-[3-(6-chloronaphthalen-... 2 0


External ID

Functional Category

Molecule Name

CFAMM00414150 CHEMBL254123 Bioactive 6-chloro-N-[1-[4-(2-cyanopyridin-3-yl)-2-fluorophenyl]-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide
CFAMM00414144 CHEMBL221475 Bioactive SureCN5223637
CFAMM00414149 CHEMBL404219 Bioactive 6-chloro-N-[1-(2-fluoro-4-pyrazol-1-ylphenyl)-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide
CFAMM00414142 CHEMBL401782 Bioactive SureCN6613850
CFAMM00414147 CHEMBL254124 Bioactive 6-chloro-N-[1-(2-fluoro-4-pyridin-4-ylphenyl)-2-oxopyrrolidin-3-yl]naphthalene-2-sulfonamide
CFAMM00414146 CHEMBL373457 Bioactive SureCN5223175

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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