CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1216
Family Name Cathepsin K and Cathepsin S inhibitor SureCN8247244 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00320687 Functional Category Bioactive
Superfamily Cathepsin K and Renin Binder Superfamily
Class Class 3310

Cousin Family NamesSeedsMembers
Matrix metalloproteinase-9 and Collagenase 3 inhibitor 4-benzy... 10 32
Cathepsin K inhibitor SureCN6578603 family 1 3
Collagenase 3 and Stromelysin-1 inhibitor 1-N-benzyl-3-N-hydro... 7 15
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R,4S)... 7 1
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R,4S)... 3 0
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 0
Neutrophil elastase inhibitor 1-[(2S)-2-[(4-methoxyphenyl)sulf... 2 11
Neutrophil collagenase and Interstitial collagenase inhibitor ... 3 0


External ID

Functional Category

Molecule Name

CFAMM00320686 CHEMBL99890 Bioactive (2R)-4-methyl-N-[2-oxo-3-[(4-phenoxyphenyl)sulfonylamino]propyl]-2-(3-phenylphenyl)pentanamide
CFAMM00320687 CHEMBL113805 Bioactive SureCN8247244

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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