CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12161
Family Name Serine/threonine-protein kinase Chk1 inhibitor (3Z)-6-(2-methyl-1,3-dihydrotetrazol-5-yl)-3-[5-(piperidin-1-ylmethyl)indol-2-ylidene]quinolin-2-one family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00414177 Functional Category Bioactive
Superfamily Cruzipain and Cytochrome P450 2C19 Binder Superfamily
Class Class 3568

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Serine/threonine-protein kinase Chk1 inhibitor SureCN14402832 ... 6 5
Serine/threonine-protein kinase Chk1 inhibitor 3-[5-(piperidin... 1 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547533 f... 3 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN5551829 f... 1 14
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 2 0
Gonadotropin-releasing hormone receptor ligand SureCN7899418 f... 12 4
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414177 CHEMBL221603 Bioactive (3Z)-6-(2-methyl-1,3-dihydrotetrazol-5-yl)-3-[5-(piperidin-1-ylmethyl)indol-2-ylidene]quinolin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24530 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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