CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12165
Family Name Dual specificity mitogen-activated protein kinase kinase 1 and Mitogen-activated protein kinase kinase kinase 1 inhibitor (2E,5R,6S,8Z,10S,11S)-17-(ethylamino)-5,6,15-trihydroxy-10,11-dimethyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,8,15,17-pentaene-7,13-dione family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00414195 Functional Category Bioactive
Superfamily Niemann-Pick C1 protein and Ras-related protein Rab-9A Binder Superfamily 10
Class Class 4891

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 4 ligand AGN-PC-087VMU family 1 4
G-protein coupled receptor 35 and Cellular tumor antigen p53 l... 1 1
2-carboxy-5-[[(E)-3-(4-methoxyphenyl)-3-oxoprop-1-enyl]amino]p... 1 0


External ID

Functional Category

Molecule Name

CFAMM00414195 CHEMBL2216826 Bioactive (2E,5R,6S,8Z,10S,11S)-17-(ethylamino)-5,6,15-trihydroxy-10,11-dimethyl-12-oxabicyclo[12.4.0]octadeca-1(14),2,8,15,17-pentaene-7,13-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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