CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12175
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform inhibitor N-[(1S)-1-[8-chloro-2-(1,3-thiazol-4-yl)quinolin-3-yl]ethyl]-7H-purin-6-amine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00414212 Functional Category Bioactive
Superfamily Beta-lactamase and Cytochrome P450 2D6 Binder Superfamily 2
Class Class 3543

Cousin Family NamesSeedsMembers
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Aurora kinase B and Aurora kinase A inhibitor AGN-PC-07ZBLC fa... 3 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M88D fa... 2 1
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 1
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
Tyrosine-protein kinase JAK2 and Cytochrome P450 3A4 inhibitor... 1 1
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 5-[5-chloro-... 2 18
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Transient receptor potential cation channel subfamily V member... 9 13
Epidermal growth factor receptor ligand AGN-PC-00RWHW family 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414212 CHEMBL2216889 Bioactive N-[(1S)-1-[8-chloro-2-(1,3-thiazol-4-yl)quinolin-3-yl]ethyl]-7H-purin-6-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26844 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543