CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12183
Family Name Proto-oncogene tyrosine-protein kinase Src inhibitor AGN-PC-00RYUW family
No. of Seeds 3 No. of Other Members 20
Family Centroid CFAMM00414243 Functional Category Bioactive
Superfamily Tyrosine-protein kinase ABL1 and Proto-oncogene tyrosine-protein kinase Src Binder Superfamily 2
Class Class 4538

Cousin Family NamesSeedsMembers
Proto-oncogene tyrosine-protein kinase Src Inhibitor 7-(naphth... 1 6
Bifunctional epoxide hydrolase 2 and Prostaglandin G/H synthas... 7 20
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Tyrosine-protein kinase ABL1 inhibitor AGN-PC-00AWSY family 13 3
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 3 8
Tyrosine-protein kinase ABL1 inhibitor SureCN4264171 family 2 0
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C9 l... 2 5
Proto-oncogene tyrosine-protein kinase Src inhibitor 7-(2,6-di... 3 0


External ID

Functional Category

Molecule Name

CFAMM00414243 CHEMBL231218 Bioactive AGN-PC-00RYUW
CFAMM00414230 CHEMBL221742 Bioactive N-[4-[[7-(2,6-dimethylphenyl)-5-methyl-1,2,4-benzotriazin-3-yl]amino]phenyl]-2-pyrrolidin-1-ylethanesulfonamide
CFAMM00414240 CHEMBL231237 Bioactive SureCN4268375

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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