CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12193
Family Name P2X purinoceptor 7 inhibitor AGN-PC-050YWL family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00414325 Functional Category Bioactive
Superfamily P2X purinoceptor 7 Binder Superfamily 4
Class Class 1375

Cousin Family NamesSeedsMembers
Neuromedin-K receptor Ligand Osanetant Family 38 192
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 7 Ligand UCM-5600 Family 15 46
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
P2X purinoceptor 7 inhibitor AGN-PC-050YNC family 1 6
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
P2X purinoceptor 7 inhibitor SureCN3659568 family 3 0
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
P2X purinoceptor 7 inhibitor SureCN3652181 family 1 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[5-... 3 0
Progesterone receptor ligand SureCN3031001 family 8 40
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414322 CHEMBL2218179 Bioactive SureCN3651868
CFAMM00414325 CHEMBL2218151 Bioactive AGN-PC-050YWL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27425 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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