CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM122
Family Name Reverse transcriptase/RNaseH inhibitor AC1LALKM family
No. of Seeds 2 No. of Other Members 19
Family Centroid CFAMM00307504 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 and Alpha-1A adrenergic receptor Binder Superfamily
Class Class 1163

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Smoothened homolog Inhibitor LDE225 Family 3 76
Glucokinase Inhibitor GKA1 Family 2 67
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Hepatocyte growth factor receptor Ligand BMS-777607 Family 10 1
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
5-hydroxytryptamine receptor 2C Ligand 4-(piperazin-1-yl)furo[... 3 11
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Hepatocyte growth factor receptor ligand SureCN4492034 family 2 2
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 2
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
Reverse transcriptase/RNaseH inhibitor Dipyridodiazepinone der... 1 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
Reverse transcriptase/RNaseH and Cytochrome P450 2C19 inhibito... 7 2
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
MAP kinase-activated protein kinase 2 inhibitor N-[4-(4-oxospi... 3 0
Melanin-concentrating hormone receptor 1 ligand N-[1-(1,3-benz... 2 5
Growth hormone secretagogue receptor type 1 and Potassium volt... 3 0
Growth hormone secretagogue receptor type 1 and Potassium volt... 2 0
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 10 13
Motilin receptor ligand SureCN2768193 family 2 1
Motilin receptor ligand SureCN2765637 family 1 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 1
Hepatocyte growth factor receptor ligand 4-pyridone analogue, ... 8 0
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 2 2
Histamine H3 receptor ligand AGN-PC-03Z8HB family 3 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00307504 CHEMBL102166 Bioactive AC1LALKM
CFAMM00307489 CHEMBL319277 Bioactive AC1LALIP

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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