CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12208
Family Name P2X purinoceptor 7 inhibitor SureCN3659568 family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00414413 Functional Category Bioactive
Superfamily P2X purinoceptor 7 Binder Superfamily 4
Class Class 1375

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
Phospholipase D1 Inhibitor Halopemide Family 17 111
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanocortin receptor 4 ligand SureCN6183720 family 2 5
P2X purinoceptor 7 inhibitor AGN-PC-050YNC family 1 6
P2X purinoceptor 7 inhibitor SureCN3726471 family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-088GOO family 3 0
P2X purinoceptor 7 inhibitor AGN-PC-050YWL family 2 4
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
P2X purinoceptor 7 inhibitor SureCN3721807 family 3 0
P2X purinoceptor 7 inhibitor SureCN3652181 family 1 0
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 2-[5-... 3 0
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2


External ID

Functional Category

Molecule Name

CFAMM00414413 CHEMBL2218581 Bioactive SureCN3659568
CFAMM00414412 CHEMBL2218583 Bioactive SureCN3655479
CFAMM00414411 CHEMBL2218582 Bioactive SureCN3649286

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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