CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1224
Family Name Thromboxane A2 receptor ligand AC1NSKJR family
No. of Seeds 13 No. of Other Members 42
Family Centroid CFAMM00320777 Functional Category Bioactive with Natural Product
Superfamily Thromboxane A2 receptor and Caspase-1 Binder Superfamily
Class Class 2020

Cousin Family NamesSeedsMembers
Eluxadoline family 4 85
Integrin beta-3 and Integrin alpha-V inhibitor 2-[(2S)-7-[1H-b... 3 6
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 20 28
Thromboxane A2 receptor ligand SureCN9045130 family 4 32
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 10 54
Thyroid hormone receptor beta ligand CHEMBL1325165 family 1 6
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
NS5B protein inhibitor (2E)-1-cyclohexyl-2-(2-fluoro-4-oxocycl... 2 10
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 4 29
Prostaglandin D2 receptor 2 ligand 2-[2-[(5-acetyl-2-methoxyph... 11 16
Type-1 angiotensin II receptor ligand N-[2-(3-methoxyphenyl)et... 2 0
Coagulation factor X inhibitor AGN-PC-07C10A family 3 2
Thromboxane A2 receptor ligand SureCN9046307 family 1 0
NS5B protein and Genome polyprotein inhibitor AC1LAG00 family 1 19
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
Gastrin/cholecystokinin type B receptor ligand AGN-PC-077L8M f... 24 10
Rho-associated protein kinase 2 inhibitor AGN-PC-078WHL family 3 1
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07C5JC family 1 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
NS5B protein inhibitor AGN-PC-00HCFC family 1 1


External ID

Functional Category

Molecule Name

CFAMM00320820 CHEMBL117821 Bioactive SureCN9044183
CFAMM00320819 CHEMBL115238 Bioactive SureCN9047177
CFAMM00320786 CHEMBL432602 Bioactive SureCN9044678
CFAMM00320812 CHEMBL115224 Bioactive SureCN9045693
CFAMM00320779 CHEMBL424621 Bioactive SureCN9044720
CFAMM00320798 CHEMBL325032 Bioactive SureCN9045471
CFAMM00320778 CHEMBL324965 Bioactive SureCN9045033
CFAMM00320777 CHEMBL422964 Bioactive AC1NSKJR
CFAMM00320790 CHEMBL117943 Bioactive SureCN9046772
CFAMM00320789 CHEMBL333159 Bioactive SureCN9046145
CFAMM00320767 CHEMBL114034 Bioactive SureCN9046679
CFAMM00320782 CHEMBL431075 Bioactive SureCN9044454
CFAMM00320808 CHEMBL116342 Bioactive SureCN9046074

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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