CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12244
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform inhibitor PIK-75 family
No. of Seeds 7 No. of Other Members 10
Family Centroid CFAMM00414613 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Binder Superfamily
Class Class 4898

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Cyclin-dependent kinase 1 inhibitor 4-[[4-(3H-benzimidazol-5-y... 1 0
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 4 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414618 CHEMBL224769 Bioactive SureCN6221072
CFAMM00414610 CHEMBL556399 Bioactive PIK-75 Hydrochloride
CFAMM00414621 CHEMBL535170 Bioactive N-[(E)-(6-fluoroimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide;hydrochloride
CFAMM00414607 CHEMBL559361 Bioactive N,2-dimethyl-N-[(E)-(6-methylimidazo[1,2-a]pyridin-3-yl)methylideneamino]-5-nitrobenzenesulfonamide;hydrochloride
CFAMM00414613 CHEMBL393525 Bioactive PIK-75
CFAMM00414606 CHEMBL555968 Bioactive N-[(E)-(6-cyanoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide;hydrochloride
CFAMM00414619 CHEMBL223071 Bioactive SureCN6221594

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543