CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12246
Family Name Peroxisome proliferator-activated receptor gamma and Peroxisome proliferator-activated receptor alpha ligand 3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-[(pyrazin-2-yloxycarbonylamino)methyl]phenyl]propanoic acid family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00067304 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Pol polyprotein Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Pristinamycin family 2 2
Egl nine homolog 2 Inhibitor FG-4592 Family 1 4
Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Melatonin receptor type 1B Ligand N-(3-benzooxazol-7-yl-propyl... 26 101
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Fatty-acid amide hydrolase 1 Inhibitor 1-(oxazolo[4,5-b]pyridi... 19 34
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
Leukotriene A-4 hydrolase Inhibitor 2-[4-(2-azepan-1-ylethoxy)... 5 15
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Renin Inhibitor CP-305202 Family 9 30
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 4
Fatty-acid amide hydrolase 1 Inhibitor 3-(benzo[d]oxazol-2-yl)... 1 6
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Muscarinic acetylcholine receptor M3 ligand [(3R)-1-[3-(1,3-be... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 21
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 13 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 4 14
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
Prelamin-A/C inhibitor CHEMBL1374443 family 1 6
Glycogen phosphorylase, liver form and Glycogen phosphorylase,... 8 9
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Inosine-5'-monophosphate dehydrogenase inhibitor SureCN1318237... 2 12
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
Prostaglandin D2 receptor ligand 2-methoxy-N-[2-(4-methoxyphen... 2 2
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Neprilysin and Natriuretic peptides A inhibitor (2S)-2-[[1-[[(... 3 3
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 4 1
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,4S)-4-f... 4 7
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[6-propan-2-ylo... 1 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 14 24
Sphingosine 1-phosphate receptor 1 ligand AGN-PC-00DWQL family 2 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 1 3
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Peroxisome proliferator-activated receptor alpha and Peroxisom... 5 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[2-(die... 12 2
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 1
Caspase-1 inhibitor (3S)-3-[[2-[3-(naphthalene-2-carbonylamino... 1 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 3 15
Pol polyprotein inhibitor Tertiary Amide deriv. 58 family 1 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2
Leukotriene A-4 hydrolase inhibitor SureCN3030546 family 9 1
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 3
cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmo... 7 2
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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