CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12248
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Protein farnesyltransferase subunit beta inhibitor AGN-PC-03EHEM family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00414627 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily H member 2 Ligand (1r,5r)-30-oxo-19-oxa-2,6,10,12-tetraazahexacyclo[18.6.2.1^{2,5}.1^{14,18}.0^{8, 12}.0^{23,27}]triaconta-8,10,14(29),15,17,20(28),21,23(27)-octaene-17-carbonitri Le (structural Mix) Superfamily
Class Class 1096

Cousin Family NamesSeedsMembers
14-alpha sterol demethylase inhibitor imidazole derivative Mi... 6 59
Aromatase Inhibitor 3-((1h-imidazol-1-yl)methyl)-9h-xanthen-9-... 6 17
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
Aromatase inhibitor AGN-PC-075MOK family 1 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 2
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 5 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414627 CHEMBL22319 Bioactive AGN-PC-03EHEM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27399 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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