CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12251
Family Name Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inhibitor 17k family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00414641 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 Binder Superfamily 6
Class Class 2014

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Serine/threonine-protein kinase Chk1 inhibitor Chk1_49 family 6 0
Serine/threonine-protein kinase Chk1 and Ribosomal protein S6 ... 4 1
Serine/threonine-protein kinase Chk1 inhibitor N-pyrazinylurea... 1 9
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-046QRM f... 1 2
Serine/threonine-protein kinase Chk1 inhibitor CHEMBL400574 fa... 26 4
Serine/threonine-protein kinase Chk1 inhibitor macrocyclic inh... 24 0
Serine/threonine-protein kinase Chk1 inhibitor CHEMBL398875 fa... 6 0
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-076BW0 f... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414644 CHEMBL249971 Bioactive CHEMBL249971
CFAMM00414643 CHEMBL374416 Bioactive macrocyclic inhibitor 17l
CFAMM00414642 CHEMBL375144 Bioactive macrocyclic inhibitor 17n
CFAMM00414641 CHEMBL223347 Bioactive macrocyclic inhibitor 17k

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27298 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543