CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12257
Family Name Protein kinase C delta type and Protein kinase C beta type inhibitor AGN-PC-071GTT family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00414659 Functional Category Bioactive
Superfamily Protein kinase C alpha type and Protein kinase C beta type Binder Superfamily
Class Class 863

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Family 1 42
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Neutrophil elastase Inhibitor E-6-o-p-methoxycinnamoyl Scandos... 2 68
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 19
Protein kinase C alpha type inhibitor [(4E)-4-[(4-fluorophenyl... 4 66
Protein kinase C alpha type inhibitor [2-(hydroxymethyl)-5-oxo... 2 4
Protein kinase C delta type and Protein kinase C alpha type in... 1 10
Protein kinase C alpha type inhibitor [(4E)-4-[(4-chloro-3-flu... 5 7
Protein kinase C alpha type inhibitor [(4E)-4-[(3-bromo-4-fluo... 3 5
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
[(1S,2S,5R)-2-hydroxy-2-methyl-5-prop-1-en-2-ylcyclohexyl] ben... 1 2
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
Putative NP ZINC00277961 Family 3 1
4-hydroxy-2-(4-methoxycarbonylphenyl)-4-methyl-6-oxocyclohexan... 15 2
ethoxy-[6-[ethoxy(oxido)methylidene]-3,7-dioxo-1,5-dihydro-s-i... 1 0


External ID

Functional Category

Molecule Name

CFAMM00414659 CHEMBL522428 Bioactive AGN-PC-071GTT
CFAMM00414665 CHEMBL472520 Bioactive [(4Z)-4-heptylidene-2-(hydroxymethyl)-5-oxooxolan-2-yl]methyl 2,4,6-tri(propan-2-yl)benzoate
CFAMM00414657 CHEMBL223747 Bioactive [2-(hydroxymethyl)-5-oxo-4-propan-2-ylideneoxolan-2-yl]methyl 4-[2-(4-ethynylphenyl)ethynyl]benzoate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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