CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12261
Family Name Adenosine receptor A1 ligand ethyl 1-(2-chloro-2-phenylethyl)-4-[2-(4-methoxyphenyl)ethylamino]pyrazolo[3,4-b]pyridine-5-carboxylate family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00126239 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase B-raf and cGMP-specific 3',5'-cyclic phosphodiesterase Binder Superfamily
Class Class 2087

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Avanafi... 3 16
Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
MK-6096 family 3 69
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Cartazo... 11 105
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 28
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 3 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Adenosine receptor A3 ligand CHEMBL1834703 family 2 1
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Mast/stem cell growth factor receptor Kit and Epithelial disco... 3 0
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(4-methoxyphenyl)... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 5 0
Adenosine receptor A3 and Adenosine receptor A1 ligand N-[2-(4... 3 2
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 13
Tyrosine-protein kinase Lck inhibitor AGN-PC-07R5ZB family 4 3
Cannabinoid receptor 1 ligand AGN-PC-07CO0E family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414686 CHEMBL8410 Bioactive SureCN7958726
CFAMM00414687 CHEMBL8198 Bioactive SureCN7955086

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26833 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543