CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12270
Family Name Angiotensin-converting enzyme inhibitor 1-[(2R,4R)-4-carboxy-2-methyl-6-phenylhexanoyl]-2,3-dihydroindole-2-carboxylic acid family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00414792 Functional Category Bioactive
Superfamily Angiotensin-converting enzyme and Neprilysin Binder Superfamily
Class Class 3583

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 2 13
Integrin beta-3 Inhibitor L-750034 Family 7 38
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Protein kinase C eta type and Protein kinase C delta type Inhi... 9 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)pheny... 2 3
D(4) dopamine receptor and D(2) dopamine receptor ligand methy... 2 11
Angiotensin-converting enzyme inhibitor AGN-PC-074KD3 family 2 0
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Angiotensin-converting enzyme inhibitor (2S)-1-[(2S)-2-sulfany... 7 23
Pol polyprotein inhibitor Lysine Sulfonamide 11o family 2 6
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[(1-benz... 5 2
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Angiotensin-converting enzyme inhibitor 2-(N-[(2S)-6-amino-2-[... 2 1
Angiotensin-converting enzyme inhibitor 89177-63-9 family 2 0
Aldose reductase and Alcohol dehydrogenase [NADP(+)] inhibitor... 2 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414792 CHEMBL22430 Bioactive 1-[(2R,4R)-4-carboxy-2-methyl-6-phenylhexanoyl]-2,3-dihydroindole-2-carboxylic acid
CFAMM00414791 CHEMBL419649 Bioactive (2S)-1-[(2R)-4-carboxy-2-methyl-6-phenylhexanoyl]-2,3-dihydroindole-2-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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