CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12275
Family Name Neprilysin inhibitor (2S)-2-[[1-[3-(4-fluorophenyl)propylcarbamoyl]cyclopentyl]methyl]-4-methoxybutanoic acid family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00414809 Functional Category Bioactive
Superfamily Neprilysin and Neuraminidase Binder Superfamily
Class Class 3396

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Neprilysin inhibitor SureCN5924965 family 1 3
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2S,4R)... 5 8
Neprilysin inhibitor SureCN7437961 family 2 6
Chymase and Chymotrypsinogen B inhibitor AGN-PC-075LTI family 2 3


External ID

Functional Category

Molecule Name

CFAMM00414809 CHEMBL224670 Bioactive (2S)-2-[[1-[3-(4-fluorophenyl)propylcarbamoyl]cyclopentyl]methyl]-4-methoxybutanoic acid
CFAMM00414812 CHEMBL225085 Bioactive SureCN1620495

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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