CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12279
Family Name Estrogen receptor ligand 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[4-[4-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenoxy]butanoylamino]methyl]benzoic acid family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00414821 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Ligand Risperidone Consta Superfamily
Class Class 544

Cousin Family NamesSeedsMembers
Microsomal triglyceride transfer protein large subunit Inhibit... 3 103
Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
cAMP-dependent protein kinase type II-beta regulatory subunit ... 34 81
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
Peroxisome proliferator-activated receptor gamma and Peroxisom... 2 4
Oxytocin receptor and Vasopressin V1a receptor Ligand D[thr4,l... 19 6
E3 ubiquitin-protein ligase XIAP Inhibitor ARPFAQK-FAM Family 2 2
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Peroxisome proliferator-activated receptor delta and Peroxisom... 20 8
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 10 8
Glutamate carboxypeptidase 2 inhibitor (2S)-2-[[[(2S)-2-carbox... 1 0
Peroxisome proliferator-activated receptor gamma ligand (9aS)-... 4 44
Peroxisome proliferator-activated receptor delta and Peroxisom... 13 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 2
C-C chemokine receptor type 3 ligand N-[(3R)-1-[(6-fluoronapht... 1 4
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 4 3
Inosine-5'-monophosphate dehydrogenase 2 inhibitor (E)-6-(4-hy... 1 10
Inosine-5'-monophosphate dehydrogenase 2 and Inosine-5'-monoph... 1 14


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414821 CHEMBL22486 Bioactive 2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[[4-[4-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenoxy]butanoylamino]methyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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