CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1229
Family Name 5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine receptor 3B ligand SureCN7273112 family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00320873 Functional Category Bioactive
Superfamily Beta-lactamase and D(2) dopamine receptor Binder Superfamily
Class Class 220

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Dopamine receptor Ligand Domperidone Family 2 21
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Motilin receptor Ligand GSK962040 Family 30 457
Sigma non-opioid intracellular receptor 1 Ligand MS-377 Family 1 21
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Nociceptin receptor Ligand J-113397 Family 3 14
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-[bis(4-iodophenyl)methyl]-3-(4... 4 13
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Induced myeloid leukemia cell differentiation protein Mcl-1 an... 2 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
Tyrosinase Inhibitor 1-hydroxy-3-(4-(trifluoromethyl)phenyl)ur... 2 3
Trypsin Inhibitor 1,3-di-p-tolyl-[1,3]diazetidine-2,4-dione Fa... 2 16
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 4 18
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 5 2
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 6 12
Cannabinoid receptor 2 ligand SureCN738026 family 5 68
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 14
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 4 6
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 3
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 3 1
Translocator protein inhibitor CHEMBL2332254 family 6 1
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-cyclo... 3 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 3 5
Cannabinoid receptor 2 ligand SureCN738244 family 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 1 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 2 1
Type-2 angiotensin II receptor ligand SureCN3515537 family 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00320873 CHEMBL114387 Bioactive SureCN7273112
CFAMM00320872 CHEMBL333144 Bioactive SureCN7282608
CFAMM00320871 CHEMBL114093 Bioactive SureCN7274000

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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