CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12292
Family Name Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydroxypyrrolidin-1-yl]methyl]piperazin-1-yl]-2-(3,5-difluorophenyl)ethanone family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00414871 Functional Category Bioactive
Superfamily Kappa-type opioid receptor Binder Superfamily 3
Class Class 634

Cousin Family NamesSeedsMembers
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
Bavisant family 9 65
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 10 52
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 3 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 5 11
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 6
Dipeptidyl peptidase 4 inhibitor (3R)-4-[(3R)-3-amino-4-(2,4,5... 6 6
Kappa-type opioid receptor and Delta-type opioid receptor liga... 9 0
Histamine H3 receptor ligand N-ethyl-3-fluoro-3-[3-fluoro-4-(p... 3 0
Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydro... 1 1
Prolyl endopeptidase inhibitor [(2S)-2-(pyrrolidine-1-carbonyl... 3 0
Kappa-type opioid receptor ligand SureCN5629426 family 3 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414873 CHEMBL23607 Bioactive 1-[4-acetyl-2-[[(3S)-3-hydroxypyrrolidin-1-yl]methyl]piperazin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
CFAMM00414871 CHEMBL22544 Bioactive 1-[4-acetyl-2-[[(3S)-3-hydroxypyrrolidin-1-yl]methyl]piperazin-1-yl]-2-(3,5-difluorophenyl)ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48716 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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