CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12295
Family Name Adenosine kinase inhibitor 5-(4-bromophenyl)-6-[2-[4-(dimethylamino)phenyl]ethynyl]pyrimidin-4-amine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00414885 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 and Beta-lactamase Binder Superfamily
Class Class 3062

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Transient receptor potential cation channel subfamily V member... 15 457
Reverse transcriptase Inhibitor Dapivirine Family 5 72
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
5-hydroxytryptamine receptor 2B Ligand MT-500 Family 8 39
Epidermal growth factor receptor and Receptor tyrosine-protein... 11 138
Peptide deformylase, mitochondrial Inhibitor 5-phenethyl-quina... 5 14
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand N*4*-(3-bromo-phenyl)-... 7 11
Epidermal growth factor receptor Ligand Benzo[g]quinazolin-4-y... 5 3
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Adenosine receptor A3 Ligand 1-(2-(diethylamino)quinazolin-4-y... 2 9
Cathepsin K Inhibitor 4-phenyl-6-propylpyrimidine-2-carbonitri... 6 10
Adenosine receptor A1 and Adenosine receptor A2a Ligand 4-amin... 4 11
Macrophage migration inhibitory factor Inhibitor 4-iodo-6-phen... 5 4
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Metabotropic glutamate receptor 5 Ligand 2-(3-bromophenyl)-7-m... 3 1
Corticotropin-releasing factor receptor 1 ligand 4-N-(2-bromo-... 9 48
Corticotropin-releasing factor receptor 1 ligand N-(2-bromo-4-... 5 0
Adenosine kinase inhibitor abt-702 family 14 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 8
Corticotropin-releasing factor receptor 1 ligand AGN-PC-01ZUJC... 2 1
Corticotropin-releasing factor receptor 1 ligand 3-(2-bromo-4-... 13 34
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 2
Dihydrofolate reductase inhibitor AC1LAKQL family 3 1
Corticotropin-releasing factor receptor 1 ligand AGN-PC-00GBP0... 3 1
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 15 3
Corticotropin-releasing factor receptor 1 ligand 9-(2-bromo-4-... 5 2
Corticotropin-releasing factor receptor 1 ligand SureCN8181501... 4 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-008HTV... 2 1
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 14 14
Epidermal growth factor receptor ligand (E)-1-[4-(3-bromoanili... 9 0
Epidermal growth factor receptor ligand AGN-PC-078X9P family 4 0
Adenosine kinase inhibitor AGN-PC-074DKZ family 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414885 CHEMBL225695 Bioactive 5-(4-bromophenyl)-6-[2-[4-(dimethylamino)phenyl]ethynyl]pyrimidin-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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