CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM123
Family Name Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,7R)-5-(1,3-benzodioxol-5-yl)-7-[4-methoxy-2-(3-methoxy-2-methylpropyl)phenyl]-2-(propan-2-ylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid family
No. of Seeds 23 No. of Other Members 8
Family Centroid CFAMM00306919 Functional Category Bioactive
Superfamily Plasminogen and Integrin beta-3 Binder Superfamily
Class Class 513

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Endothelin-1 receptor and Endothelin B receptor ligand (5S,6R,... 15 28
Endothelin-1 receptor and Endothelin B receptor ligand 3-(1,3-... 1 1
Endothelin-1 receptor and Endothelin B receptor ligand SureCN1... 3 16
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(4-ethox... 4 5
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 6 5
Integrin beta-3 and Integrin alpha-V inhibitor 2-(2,3-dihydro-... 13 1
Leukotriene B4 receptor 1 ligand SureCN8987047 family 4 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 7 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor Sure... 14 8
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-00FA9Q f... 7 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-(1,3-ben... 8 3
Integrin beta-3 and Integrin alpha-V inhibitor SureCN5849872 f... 5 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6223678 f... 14 1
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-03OERH f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00307510 CHEMBL287683 Bioactive (5S,6R,7R)-5-(1,3-benzodioxol-5-yl)-7-[2-[3-(dimethylamino)-2-methyl-3-oxopropyl]-4-methoxyphenyl]-2-(propan-2-ylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid
CFAMM00307516 CHEMBL289216 Bioactive (5S,6R,7R)-5-(1,3-benzodioxol-5-yl)-7-[2-(1-hydroxypropan-2-yloxy)-4-methoxyphenyl]-2-(propan-2-ylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid
CFAMM00307513 CHEMBL286621 Bioactive (5S,6R,7R)-5-(1,3-benzodioxol-5-yl)-7-[2-(2,3-dihydroxypropyl)-4-methoxyphenyl]-2-(propan-2-ylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid
CFAMM00307521 CHEMBL287517 Bioactive (5S,6R,7R)-5-(1,3-benzodioxol-5-yl)-7-(4-methoxy-2-phenylmethoxyphenyl)-2-(propan-2-ylamino)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46031 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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