CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12307
Family Name Adenosine receptor A3 ligand (2R,3R,4S)-2-[2-chloro-6-[(3-fluorophenyl)methylamino]purin-9-yl]thiolane-3,4-diol family
No. of Seeds 6 No. of Other Members 7
Family Centroid CFAMM00414930 Functional Category Bioactive
Superfamily Adenosine receptor A3 and Adenosine receptor A1 Binder Superfamily 3
Class Class 3391

Cousin Family NamesSeedsMembers
Toll-like receptor 7 Ligand Imiquimod Family 3 237
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
P2Y purinoceptor 12 Inhibitor Brilinta Family 1 1
Adenosine receptor A3 Ligand CF101 Family 24 560
Adenosine receptor A2a Ligand MRE-0094 Family 10 108
Adenosine receptor A1 Ligand SLV320 Family 6 79
GDC-0349 family 44 77
Equilibrative nucleoside/nucleobase transporter Inhibitor Nitr... 23 98
Poly [ADP-ribose] polymerase 1 Inhibitor EB-47 Family 17 41
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 2 7
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 7 72
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Adenosine receptor A1 and Adenosine receptor A2a Ligand N6-met... 21 57
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-[(4-... 15 9
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 12 5
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(3''... 2 2
Adenosine receptor A2a and Adenosine receptor A3 Ligand 2-(3''... 8 10
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Inositol 1,4,5-trisphosphate receptor type 3 Ligand 5'-deoxy-5... 11 8
Adenosine kinase inhibitor GP683 family 12 7
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 17 17
Adenosine receptor A1 and Adenosine receptor A2a ligand (2S,3S... 2 16
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase inh... 7 6
S-methyl-5'-thioadenosine phosphorylase inhibitor SureCN997478... 8 0
Adenosine receptor A3 and Adenosine receptor A2a ligand (1R,2R... 12 17
Adenosine receptor A1 ligand N-[(2R,3R,4R,5R)-5-[6-(cyclopenty... 3 2
Adenosine kinase inhibitor 2-[[7-[(2R,3R,4S,5R)-3,4-dihydroxy-... 15 0
Adenosine kinase inhibitor SureCN8320660 family 7 2
Adenosine receptor A3 and Adenosine receptor A1 ligand (2S,3S,... 8 10
Dual specificity protein kinase TTK inhibitor 4-[[2-(2-methyl-... 1 0
S-methyl-5'-thioadenosine phosphorylase inhibitor 2-[[(4-amino... 5 0
Adenosine receptor A3 ligand (1R,2R,3S,4R,5S)-4-[2-[2-(2-chlor... 5 1
Tyrosine-protein kinase JAK1 and Non-receptor tyrosine-protein... 7 0
Adenosine receptor A3 ligand (2R,3R,4S)-2-[6-[(3-bromophenyl)m... 3 0
Adenosine receptor A1 ligand N-butyl-5-phenyl-3-[[2-(trifluoro... 7 2
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Adenosine receptor A1 ligand 2-[4-[[2-[4-[[9-[(3R,4S,5R)-3,4-d... 14 0
Serine/threonine-protein kinase mTOR inhibitor 1-ethyl-3-[4-[6... 4 1
Adenosine receptor A1 ligand 3-chloro-N-[(2S,3R,4R,5R)-5-[6-(c... 1 0
Adenosine receptor A1 ligand N-[(2R,3R,4R,5R)-5-[6-(cyclopenty... 3 3
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand (2R,3R,... 1 0
Equilibrative nucleoside transporter 1 inhibitor N-[6-[2-[[(2S... 2 0
Adenosine receptor A2a and Adenosine receptor A2b ligand (3S,4... 3 2
DNA polymerase III PolC-type and DNA polymerase III subunit al... 11 10
78 kDa glucose-regulated protein and Heat shock cognate 71 kDa... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414930 CHEMBL226581 Bioactive (2R,3R,4S)-2-[2-chloro-6-[(3-fluorophenyl)methylamino]purin-9-yl]thiolane-3,4-diol
CFAMM00414925 CHEMBL387921 Bioactive (2R,3R,4S)-2-[2-chloro-6-[(3-chlorophenyl)methylamino]purin-9-yl]thiolane-3,4-diol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

41178 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543