CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12314
Family Name Acyl-CoA desaturase 1 inhibitor 3-[4-(2-chlorophenoxy)piperidin-1-yl]-6-pyridin-3-ylpyridazine family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00414945 Functional Category Bioactive
Superfamily Hepatocyte growth factor receptor and Proto-oncogene tyrosine-protein kinase ROS Inhibitor Crizotinib Superfamily
Class Class 795

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Hepatocyte growth factor receptor Ligand Amg 208 Family 20 236
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-072YXQ ... 2 1
Adenosine receptor A3 ligand CHEMBL1834696 family 5 18
Acyl-CoA desaturase and Acyl-CoA desaturase 1 inhibitor 6-(5-f... 7 15
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 3 0
Epidermal growth factor receptor and Receptor tyrosine-protein... 6 9
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 4 9
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 3
Stearoyl-CoA desaturase 5 and Acyl-CoA desaturase inhibitor 5-... 2 10
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 3 0
Acyl-CoA desaturase 1 inhibitor 6-[4-(2-chlorophenoxy)piperidi... 7 3
Receptor tyrosine-protein kinase erbB-2 and Epidermal growth f... 14 3
Epidermal growth factor receptor and Receptor tyrosine-protein... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00414945 CHEMBL226649 Bioactive 3-[4-(2-chlorophenoxy)piperidin-1-yl]-6-pyridin-3-ylpyridazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27394 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543