CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12317
Family Name Urokinase-type plasminogen activator and Tissue-type plasminogen activator inhibitor cycloleucine deriv. 44 family
No. of Seeds 3 No. of Other Members 15
Family Centroid CFAMM00414961 Functional Category Bioactive
Superfamily Urokinase-type plasminogen activator and Plasminogen Binder Superfamily 2
Class Class 1128

Cousin Family NamesSeedsMembers
Plasminogen and Urokinase-type plasminogen activator Inhibitor... 3 26
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
Urokinase-type plasminogen activator and Plasminogen inhibitor... 6 4
Suppressor of tumorigenicity 14 protein and Prothrombin inhibi... 1 3


External ID

Functional Category

Molecule Name

CFAMM00414961 CHEMBL228113 Bioactive cycloleucine deriv. 44
CFAMM00414964 CHEMBL226714 Bioactive cycloleucine deriv. 45
CFAMM00414970 CHEMBL227931 Bioactive cycloleucine deriv. 43

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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