CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12333
Family Name Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter inhibitor 2-[(1S,3S,4S,5R)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-4-yl]-5-(3-nitrophenyl)-1,3-thiazole family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00264629 Functional Category Bioactive
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor RTI-219 Superfamily
Class Class 2415

Cousin Family NamesSeedsMembers
Cytochrome P450 3A4 Inhibitor 3-(3-methylthiophen-2-yl)pyridin... 5 27
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 16
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 12
D(4) dopamine receptor ligand SureCN8706945 family 4 10
Sodium-dependent serotonin transporter and D(4) dopamine recep... 2 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00415034 CHEMBL226984 Bioactive 2-[(1S,3S,4S,5R)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-4-yl]-5-(3-nitrophenyl)-1,3-thiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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