CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1236
Family Name Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YUB family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00320949 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 and Smoothened homolog Binder Superfamily
Class Class 1034

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
D(4) dopamine receptor Ligand Fauc 113 Family 14 96
D(2) dopamine receptor and D(3) dopamine receptor Ligand 1-(4-... 10 48
Calcium-activated potassium channel subunit alpha-1 Ligand 1-(... 3 3
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(1h-1,2,3-triazol-5-... 3 12
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 2 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 4 33
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 2
Corticotropin-releasing factor receptor 1 ligand AGN-PC-074YT9... 28 20
Corticotropin-releasing factor receptor 1 ligand 3,7-dimethyl-... 3 4
Smoothened homolog inhibitor AC1P6IWE family 1 0
Adenosine receptor A2b and Adenosine receptor A2a ligand CP-66... 3 33
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 2-[8-... 2 5
D(4) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 5 1
Corticotropin-releasing factor receptor 1 ligand SureCN7215846... 4 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 5 1
Adenosine receptor A1 ligand 3-[(2-chlorophenyl)methyl]-N-cycl... 1 1
Serine/threonine-protein kinase B-raf and Mitogen-activated pr... 16 5
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(2-c... 2 0
Extracellular calcium-sensing receptor ligand SureCN2220343 fa... 1 0


External ID

Functional Category

Molecule Name

CFAMM00320950 CHEMBL324728 Bioactive AGN-PC-074YU9
CFAMM00320949 CHEMBL114273 Bioactive AGN-PC-074YUB

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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