CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12360
Family Name Coagulation factor X and Prothrombin inhibitor SureCN8243313 family
No. of Seeds 10 No. of Other Members 8
Family Centroid CFAMM00415199 Functional Category Bioactive with Natural Product
Superfamily Prothrombin and Coagulation factor X Binder Superfamily 4
Class Class 913

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Farnesyltransferase beta subunit, putative Inhibitor Lonafarni... 36 87
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
ABC294640 family 5 75
Gonadotropin-releasing hormone Inhibitor ASP3550 Family 33 60
Lethal factor Inhibitor GM6001 Family 50 435
Gonadotropin-releasing hormone receptor Ligand Azaline B Family 12 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Gonadotropin-releasing hormone receptor Ligand [d-ncy(methyl)4... 32 0
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Prothrombin inhibitor SureCN7371121 family 13 3
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(6-aminopyr... 1 4
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Prothrombin inhibitor (2S)-N-[(6-carbamimidoylpyridin-3-yl)met... 2 14
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 10 0
Prothrombin and Tissue-type plasminogen activator inhibitor 2-... 4 5
Prothrombin inhibitor 1o0d family 2 0
Coagulation factor X inhibitor 6-chloro-N-[1-(2-fluoro-4-pyrid... 6 7
Coagulation factor X and Prothrombin inhibitor SureCN8237487 f... 16 1
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand N-[(1R,... 4 2


External ID

Functional Category

Molecule Name

CFAMM00415193 CHEMBL390402 Bioactive SureCN8242108
CFAMM00415199 CHEMBL228340 Bioactive SureCN8243313
CFAMM00415192 CHEMBL390403 Bioactive SureCN8237475
CFAMM00415191 CHEMBL394517 Bioactive SureCN8236176
CFAMM00415190 CHEMBL231595 Bioactive AGN-PC-0766DW
CFAMM00415202 CHEMBL228341 Bioactive SureCN8245072
CFAMM00415195 CHEMBL395773 Bioactive AGN-PC-0766DU
CFAMM00415201 CHEMBL228285 Bioactive methyl 2-[[1-[(2S)-2-[[2-(aminomethyl)-5-chlorophenyl]methylcarbamoyl]pyrrolidin-1-yl]-4-(1-oxidopyridin-1-ium-2-yl)-1-oxobutan-2-yl]amino]-2-oxoacetate
CFAMM00415194 CHEMBL229036 Bioactive SureCN8246765
CFAMM00415200 CHEMBL427464 Bioactive methyl 2-[[(2R)-1-[(2S)-2-[[2-(aminomethyl)-5-chlorophenyl]methylcarbamoyl]pyrrolidin-1-yl]-4-(1-oxidopyridin-1-ium-2-yl)-1-oxobutan-2-yl]amino]-2-oxoacetate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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