CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM12363
Family Name RAC-beta serine/threonine-protein kinase and 3-phosphoinositide-dependent protein kinase 1 inhibitor SureCN3476999 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00252501 Functional Category Bioactive
Superfamily RAC-beta serine/threonine-protein kinase and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 1941

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
DNA Binder Elliptinium Acetate Family 11 116
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Indeglitazar family 3 39
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Lethal factor Inhibitor GM6001 Family 50 435
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
Vascular endothelial growth factor receptor 1 Ligand Lycogarub... 6 292
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 12
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Acetylcholinesterase and Cholinesterase Inhibitor 6-hydroxy-1,... 4 2
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Phospholipase A2 Inhibitor Hyrtiosulawesine Family 1 3
Histone deacetylase Inhibitor ST-5732 Family 8 6
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Vascular endothelial growth factor receptor 2 and Receptor-typ... 7 4
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 8 3
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
Peroxisome proliferator-activated receptor delta and Peroxisom... 1 1
RAC-beta serine/threonine-protein kinase inhibitor SureCN57283... 2 0
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Transient receptor potential cation channel subfamily V member... 1 5
Serine/threonine-protein kinase PLK4 inhibitor (3E)-5-methoxy-... 4 0
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
KiSS-1 receptor ligand N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-... 1 0
Survival motor neuron protein and Arachidonate 15-lipoxygenase... 1 2
Microtubule-associated protein tau and Glycogen synthase kinas... 9 15
Mitogen-activated protein kinase 14 inhibitor AGN-PC-08866Z fa... 2 0
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 1 1
Lutropin-choriogonadotropic hormone receptor ligand 5-[2-(4-te... 1 1
NP 1-(3-hydroxyphenyl)-3-(1-methyl-1h-indol-3-yl)pyrrolidine-2... 4 1
1-[(5-hydroxy-1H-indol-3-yl)methyl]-5'-methyl-5-phenylspiro[1,... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22645 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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